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 Human Endocannabinoid System & Full Spectrum Synergy 
The Body's Master Regulator is the  Endocannabinoild System ("ECS")
- Cell signaling to maintain homeostasis in body systems
- Based on fatty acids or eicosannoids derived from phospholipids and arachidonic acid
Internal cannabinoids are created on demand and degraded very rapidly in the cell membrane
- Taking phytocannabinoids is shown to improve mood, flexibility, lessen pain and create body function homeostatis 

Human Studies

One 2022 study of 31 young people (aged 12-25) with treatment-resistant anxiety disorders found that CBD improved depressive symptoms (2).

Another 2018 study looked at using CBD to improve mood and other psychological symptoms associated with chronic cannabis use. Twenty frequent cannabis users took 200 mg CBD capsules taken daily for 10 weeks, resulting in improvement of depressive and psychotic symptoms (3). 

Meanwhile, a 2020 case report of a teenage boy with multiple substance use disorder, severe depression, social anxiety, and other issues found that CBD improved depressive and anxiety symptoms (4). He took pure CBD capsules for 8 weeks, starting at 100 mg and moving up to 600 mg, after ineffective treatment with the antidepressant sertraline (Zoloft) for 6 months.

Additionally, a 2014 study found that Sativex, a drug that contains equal amounts of THC and CBD, improved irritability and depressive symptoms in 51 people suffering from cannabis withdrawal (5). Although these findings are less relevant because CBD products contain relatively small amounts of THC, they still suggest some potential benefits. 

Finally, a 2021 academic book on depression summarized that “preclinical evidence suggests it [CBD] can be a promising new antidepressant” and called for further research (6). 

Products are currently available in these convenient-to-use forms


Full-spectrum, Broad Spectrum, and Raw hemp extract in calibrated dropper bottles for easy administration. Unlike many liquid hemp extracts, our professional-use products provide a calibrated glass pipette for proper dosing, removing the imprecision and hassle of counting drops. 

Additionally, with the calibrated glass dropper, our liquids offer flexibility in dosing to meet different patient needs.

Our liquid hemp extracts are also available for pets.

Liquid Vegetable Capsules

Full-spectrum, Broad spectrum, and Raw hemp extract are provided in convenient liquid-filled vegetable capsules that disintegrate quickly for rapid utilization.


Great-tasting gummies supplying full-spectrum hemp extract, some with added botanicals or other cannabinoids. Our gelatin-free gummies are suitable for vegetarians and vegans and contain no artificial colors, flavors, or sweeteners. Buckle (cheek) holding can increase the absorption of the cbd without going into the stomach for digestion. The CBD goes directly into the blood. 


ECS Therapy topicals supply hemp extract enhanced with synergistic botanicals and supporting ingredients.  Available in creams, balms, and lotions, our all-natural topicals absorb quickly into the skin and promote a cooling and soothing effect. We've carefully formulated ECS Therapy topicals to be free of known endocrine disruptors and other recognized harmful ingredients commonly found in other topical products in the market.



LouLou Tree will help provide guidance on the Botanical synergy and entourage effect from phytonutrients of botanicals during coaching and educational sessions.


To further help LLT clients', the message of key C. Sativa products help the endocannabinoid tone in older individuals, since with age we lose functioning health benefits of Cannabidiol system. 


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